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It is widely believed and in part established that exact global symmetries are inconsistent with quantum gravity. One then expects that approximate global symmetries can be quantitatively constrained by quantum gravity or swampland arguments. We provide such a bound for an important class of global symmetries: Those arising from a gauged $U(1)$ with the vector made massive via Higgsing with an axion. The latter necessarily couples to instantons, and their action can be constrained, using both the electric and magnetic version of the axionic weak gravity conjecture, in terms of the cutoff of the theory. As a result, instanton-induced symmetry breaking operators with a suppression factor not smaller than $\exp(-M_{\rm P}^2/Λ^2)$ are present, where $Λ$ is a cutoff of the 4d effective theory. We provide a general argument and clarify the meaning of $Λ$. Simple 4d and 5d models are presented to illustrate this, and we recall that this is the standard way in which things work out in string compactifications with brane instantons. The relation of our constraint to bounds that can be derived from wormholes or gravitational instantons and to those motivated by black-hole effects at finite temperature are discussed, and we present a generalization of the Giddings-Strominger wormhole solution to the case of a gauge-derived $U(1)$ global symmetry. Finally, we discuss potential loopholes to our arguments.