论文标题
基于受试者内白质纤维簇的皮质表面拟层
Cortical surface parcellation based on intra-subject white matter fiber clustering
论文作者
论文摘要
我们提出了一种混合方法,该方法基于从整个脑部拖拉数据集中的白质纤维的连通性信息,对个体的大脑皮层进行完整的分析。该方法由五个步骤组成,在脑拖拉机上进行了第一个主体内聚类。然后将组成每个群集的纤维与皮质网格相交,然后过滤以丢弃异常值。另外,该方法可以有效地解决整个皮质的不同交叉区域之间的重叠。最后,进行后处理是为了实现更多统一的子牌。输出是代表不同皮质子份量的皮质网格顶点的完整标记,并与其他子参与者有牢固的连接。我们用大脑连通性的度量(例如功能分离(聚类系数),功能积分(特征路径长度)和小世界评估了我们的方法。来自ARCHI数据库的五个受试者的结果表明,每个受试者对每个受试者的皮质细胞良好,每个半球约有200个地下参数,并遵守这些连通性测量。
We present a hybrid method that performs the complete parcellation of the cerebral cortex of an individual, based on the connectivity information of the white matter fibers from a whole-brain tractography dataset. The method consists of five steps, first intra-subject clustering is performed on the brain tractography. The fibers that make up each cluster are then intersected with the cortical mesh and then filtered to discard outliers. In addition, the method resolves the overlapping between the different intersection regions (sub-parcels) throughout the cortex efficiently. Finally, a post-processing is done to achieve more uniform sub-parcels. The output is the complete labeling of cortical mesh vertices, representing the different cortex sub-parcels, with strong connections to other sub-parcels. We evaluated our method with measures of brain connectivity such as functional segregation (clustering coefficient), functional integration (characteristic path length) and small-world. Results in five subjects from ARCHI database show a good individual cortical parcellation for each one, composed of about 200 subparcels per hemisphere and complying with these connectivity measures.