论文标题
使用对数尺寸相关性直接估算超声心动图的全局纵向应变
Direct estimation of global longitudinal strain from echocardiograms using a logarithm-scaled Fourier magnitude correlation
论文作者
论文摘要
我们提出了一种使用对数转换相关方法（LTC）方法来测量2D超声心动图的全局纵向应变和全局纵向应变速率的新方法。与传统的超声心动图菌株分析相反，我们的方法不需要心脏腔室分割和正则化。使用合成左心室超声图像对两种常规应变分析方法进行基准测试。使用平均绝对误差和根平方误差评估测量误差是对比度与噪声比率（CNR）的函数，并显示出更好的一致性菌株（$ r^2 $ = 0.91）和应变速率（$ r^2 $ = 0.85）（与常规算法相比（$ r^2 $ = 0.7），应变率（$ r^2 $ r^2）。而且，我们的方法不受CNR的影响。与常规算法相比，观察到的应变测量精度增加了200％。随后，我们使用54个受试者的临床队列（患有心肌病患病的20名受试者，34个健康对照）测试了该方法。我们的方法区分了正常和异常的左心室功能，AUC = 0.85，比常规GLS算法提高了10％。
We present a new method for measuring global longitudinal strain and global longitudinal strain rate from 2D echocardiograms using a logarithmic-transform correlation (LTC) method. In contrast to traditional echocardiography strain analysis, our approach does not require cardiac chamber segmentation and regularization. The algorithm was benchmarked against two conventional strain analysis methods using synthetic left ventricle ultrasound images. Measurement error was assessed as a function of contrast-to-noise ratio (CNR) using mean absolute error and root-mean-square error and showed better agreement to the ground truth for strain($R^2$ = 0.91) and strain rate($R^2$ = 0.85) as compared to conventional algorithms (strain($R^2$ = 0.7), strain rate($R^2$ = 0.7)). Also, our method was unaffected by CNR. A 200% increase in strain measurement accuracy was observed compared to the conventional algorithms. Subsequently, we tested the method using a 54-subject clinical cohort (20 subjects diseased with cardiomyopathy, 34 healthy controls). Our method distinguished between normal and abnormal left ventricular function with an AUC = 0.85, a 10% improvement over the conventional GLS algorithms.
