论文标题
额叶连通性神经反馈培训促进工作记忆：健康男性参与者的FNIRS研究
Frontoparietal Connectivity Neurofeedback Training for Promotion of Working Memory: An fNIRS Study in Healthy Male Participants
论文作者
论文摘要
神经反馈认知训练是一种有前途的工具，用于有效有效地促进认知功能。在这项研究中，我们研究了一个新型的功能性近红外光谱（FNIRS）基于涉及健康成年人的工作记忆相关的基于基于的基于基于健康的成年人的额叶功能连通性（FC）神经反馈训练范围。与常规的认知训练研究相比，我们选择了额产网络，这是一种用于认知功能调节的关键大脑区域，作为神经反馈，产生了强大的靶向效果。在实验中，使用基于FNIRS的额叶FC作为神经反馈，有10名参与者（测试组）接受了15分钟的3个认知训练课程，另外10位参与者担任对照组。与对照组相比，测试组（P D 0.03）的额叶FC显着增加（P D 0.03），并且认知功能（记忆和注意力）得到了显着促进的（3-back测试的准确性：P D 0.0005，3-back测试的反应时间：P D 0.0009）。在对长期训练效果和不同患者人群的其他验证之后，该建议的方法具有很大的潜力，可以作为一种快速，有效且广泛的训练方法来增强认知功能。
Neurofeedback cognitive training is a promising tool used to promote cognitive functions effectively and efficiently. In this study, we investigated a novel functional near-infrared spectroscopy (fNIRS)-based frontoparietal functional connectivity (FC) neurofeedback training paradigm related to working memory, involving healthy adults. Compared with conventional cognitive training studies, we chose the frontoparietal network, a key brain region for cognitive function modulation, as neurofeedback, yielding a strong targeting effect. In the experiment, 10 participants (test group) received three cognitive training sessions of 15 min using fNIRS-based frontoparietal FC as neurofeedback, and another 10 participants served as the control group. Frontoparietal FC was significantly increased in the test group (p D 0.03), and the cognitive functions (memory and attention) were significantly promoted compared with the control group (accuracy of 3-back test: p D 0.0005, reaction time of 3-back test: p D 0.0009). After additional validations on long-term training effect and on different patient populations, the proposed method exhibited considerable potential to be developed as a fast, effective, and widespread training approach for cognitive function enhancement.
