论文标题
COV-ELM分类器:使用胸部X射线图像的基于极端学习机器的Covid-19识别
COV-ELM classifier: An Extreme Learning Machine based identification of COVID-19 using Chest X-Ray Images
论文作者
论文摘要
冠状病毒构成引起呼吸道疾病的一系列病毒。由于COVID-19具有高度传染性,因此COVID-19的早期诊断对于有效的治疗策略至关重要。但是,被认为是诊断为COVID-19的金标准的RT-PCR检验遭受了较高的假阴性率。胸部X射线(CXR)图像分析已成为针对该目标的可行且有效的诊断技术。在这项工作中,我们提出了Covid-19分类问题作为三类分类问题,以区分Covid-19,正常和肺炎类别。我们提出了一个三阶段的框架,名为Cov-Elm。第一阶段涉及预处理和转换,而第二阶段则处理特征提取。这些提取的特征作为输入在第三阶段输入到ELM,从而识别Covid-19。与传统的基于梯度的学习算法相比,这项工作中榆树的选择是由于其更快的收敛性,更好的概括能力和较短的训练时间而动机。随着更大和多样化的数据集的可用性,与基于梯度的竞争对手模型相比,可以快速重新培训ELM。所提出的模型以95%的置信区间的形式达到了0.95的宏平均F1评分,总体灵敏度为$ {0.94 \ pm 0.02}。与最先进的机器学习算法相比,在这种三级分类方案中,COV-ELM的表现优于其竞争对手。此外,石灰已与提出的COV-ELM模型集成在一起,以生成带注释的CXR图像。注释基于有助于区分不同类别的超级像素。据观察,超级像素对应于在Covid-19和肺炎病例中临床观察到的人肺区域。
Coronaviruses constitute a family of viruses that gives rise to respiratory diseases. As COVID-19 is highly contagious, early diagnosis of COVID-19 is crucial for an effective treatment strategy. However, the RT-PCR test which is considered to be a gold standard in the diagnosis of COVID-19 suffers from a high false-negative rate. Chest X-ray (CXR) image analysis has emerged as a feasible and effective diagnostic technique towards this objective. In this work, we propose the COVID-19 classification problem as a three-class classification problem to distinguish between COVID-19, normal, and pneumonia classes. We propose a three-stage framework, named COV-ELM. Stage one deals with preprocessing and transformation while stage two deals with feature extraction. These extracted features are passed as an input to the ELM at the third stage, resulting in the identification of COVID-19. The choice of ELM in this work has been motivated by its faster convergence, better generalization capability, and shorter training time in comparison to the conventional gradient-based learning algorithms. As bigger and diverse datasets become available, ELM can be quickly retrained as compared to its gradient-based competitor models. The proposed model achieved a macro average F1-score of 0.95 and the overall sensitivity of ${0.94 \pm 0.02} at a 95% confidence interval. When compared to state-of-the-art machine learning algorithms, the COV-ELM is found to outperform its competitors in this three-class classification scenario. Further, LIME has been integrated with the proposed COV-ELM model to generate annotated CXR images. The annotations are based on the superpixels that have contributed to distinguish between the different classes. It was observed that the superpixels correspond to the regions of the human lungs that are clinically observed in COVID-19 and Pneumonia cases.