论文标题
新型冠状病毒（SARS-COV-2）感染的可检测性和新型冠状病毒感染的死亡率和俄罗斯联合会不同地区的死亡率
Detectability of the novel coronavirus (SARS-CoV-2) infection and rates of mortality from the novel coronavirus infection in different regions of the Russian Federation
论文作者
论文摘要
相关性：新型冠状病毒（SARS-COV-2）感染的实验室诊断与感染个体接触的隔离性会影响SARS-COV-2感染和相关死亡率水平的传播。 SARS-COV-2感染测试的实践在俄罗斯的地理上不同。例如，在圣彼得堡市，在2020年10月25日，俄罗斯联邦的死亡率是最高的俄罗斯联合会中的死亡率，covid-19的每一次死亡都对应于15.7个人口中的共同案例，而整个俄罗斯的相应数量是58.1的相应数量，这是58.1的58.1，表明对covit的温和案例coptecter copter copter copter copter copter copter copter copter in St. peterg in covers in covers in covers in covers in covid burg中均为coververs-burn。方法：对SARS-COV-2的更积极的测试会导致较低的病例型比率（即，在所有种群中所有SARS-COV-2感染的病例中检测到的COVID-19病例的比例）。我们使用有关COVID-19病例和死亡的数据来检查俄罗斯联邦不同地区COVID-19的病例合作比率与死亡率之间的相关性。结果：2020年10月25日，俄罗斯联邦不同地区的COVID-19的病例合法比率与死亡率之间的相关性为0.64（0.50,0.75）。对于俄罗斯联邦的几个地区，SARS-COV-2感染的可检测性相对较低，而Covid-19的死亡率相对较高。结论：SARS-COV-2感染的可检测性是影响COVID-19的死亡率水平的因素之一。为了提高可检测性，应该测试所有患有SARS-COV-2感染医疗护理的呼吸道症状的人，并采取其他措施来增加SARS-COV-2的测试量。此类措施与受感染病例的隔离结合结合使用，其密切接触有助于减轻SARS-COV-2感染的传播并降低相关死亡率。
Relevance: Laboratory diagnosis of the novel coronavirus (SARS-CoV-2) infection combined with quarantine for contacts of infected individuals affects the spread of SARS-CoV-2 infection and levels of related mortality. Practices for testing for SARS-CoV-2 infection vary geographically in Russia. For example, in the city of St. Petersburg, where mortality rate for COVID-19 is the highest in the Russian Federation on Oct. 25, 2020, every death for COVID-19 corresponds to 15.7 detected cases of COVID-19 in the population, while the corresponding number for the whole of Russia is 58.1, suggesting limited detection of mild/moderate cases of COVID-19 in St. Petersburg. Methods: More active testing for SARS-CoV-2 results in lower case-fatality ratio (i.e. the proportion of detected COVID-19 cases among all cases of SARS-CoV-2 infection in the population). We used data on COVID-19 cases and deaths to examine the correlation between case-fatality ratios and rates of mortality for COVID-19 in different regions of the Russian Federation. Results: The correlation between case-fatality ratios and rates of mortality for COVID-19 in different regions of the Russian Federation on Oct. 25, 2020 is 0.64 (0.50,0.75). For several regions of the Russian Federation, detectability of SARS-CoV-2 infection is relatively low, while rates of mortality for COVID-19 are relatively high. Conclusions: Detectability of the SARS-CoV-2 infection is one of the factors that affects the levels of mortality from COVID-19. To increase detectability, one ought to test all individuals with respiratory symptoms seeking medical care for SARS-CoV-2 infection, and to undertake additional measures to increase the volume of testing for SARS-CoV-2. Such measures, in combination with quarantine for infected cases and their close contacts help to mitigate the spread of the SARS-CoV-2 infection and diminish the related mortality.
