论文标题
美国县级Covid-19活动的高分辨率时空模型
High-resolution Spatio-temporal Model for County-level COVID-19 Activity in the U.S
论文作者
论文摘要
我们提出了一个可解释的高分辨率时空模型,以估计Covid-19的死亡人数,并在美国的县级和每周的总体汇总一周前确认案件。我们时空模型的一个值得注意的特征是,它考虑了两个本地时间序列的(a)时间自动和成对的相关性(确认的病例和COVID-19),(b)县的位置(传播)和(c)协会之间的动力学(b)诸如局部社区内部迁移率和社会性数据学因素和社会性数据学因素。社区内部的流动性和人口统计因素(例如总人口和老年人的比例)被包括为重要的预测因子,因为假设它们对于确定Covid-19的动力学很重要。为了降低模型的高维度,我们将稀疏结构施加为限制,并强调了美国十大大都市地区的影响,我们将其称为(并在模型中)是传播疾病的枢纽。我们的回顾性县外县级预测能够准确预测随后观察到的Covid-19活动。所提出的多变量预测模型被设计为高度可解释的,并清楚地识别和量化决定了COVID-19的动力学的最重要因素。正在进行的工作涉及纳入更多的协变量,例如教育和收入,以提高预测准确性并模拟可解释性。
We present an interpretable high-resolution spatio-temporal model to estimate COVID-19 deaths together with confirmed cases one-week ahead of the current time, at the county-level and weekly aggregated, in the United States. A notable feature of our spatio-temporal model is that it considers the (a) temporal auto- and pairwise correlation of the two local time series (confirmed cases and death of the COVID-19), (b) dynamics between locations (propagation between counties), and (c) covariates such as local within-community mobility and social demographic factors. The within-community mobility and demographic factors, such as total population and the proportion of the elderly, are included as important predictors since they are hypothesized to be important in determining the dynamics of COVID-19. To reduce the model's high-dimensionality, we impose sparsity structures as constraints and emphasize the impact of the top ten metropolitan areas in the nation, which we refer (and treat within our models) as hubs in spreading the disease. Our retrospective out-of-sample county-level predictions were able to forecast the subsequently observed COVID-19 activity accurately. The proposed multi-variate predictive models were designed to be highly interpretable, with clear identification and quantification of the most important factors that determine the dynamics of COVID-19. Ongoing work involves incorporating more covariates, such as education and income, to improve prediction accuracy and model interpretability.