论文标题

尺寸依赖性的粒子迁移并陷入3D微泡流中

Size-dependent particle migration and trapping in 3D microbubble streaming flows

论文作者

Volk, Andreas, Rossi, Massimiliano, Rallabandi, Bhargav, Kaehler, Christian J., Hilgenfeldt, Sascha, Marin, Alvaro

论文摘要

声学作用的无柄气泡可以用作操纵微粒,囊泡和细胞的工具。在这项工作中,使用声学驱动的无梗半圆柱形微泡,我们通过实验证明有限尺寸的微粒经历尺寸敏感的迁移,并在具有高可重复性的三个维度中捕获了特定的空间位置。粒子在稳定的三维流动流场中的被动对流成功地复制了粒子轨迹,并增加了限制边界的体积排除。对于不同的粒径,该体积排除机制导致了三种质量不同的迁移行为的制度,这表明将颗粒分离,捕获和排序的应用在三个维度上。

Acoustically actuated sessile bubbles can be used as a tool to manipulate microparticles, vesicles and cells. In this work, using acoustically actuated sessile semi-cylindrical microbubbles, we demonstrate experimentally that finite-sized microparticles undergo size-sensitive migration and trapping towards specific spatial positions in three dimensions with high reproducibility. The particle trajectories are successfully reproduced by passive advection of the particles in a steady three-dimensional streaming flow field augmented with volume exclusion from the confining boundaries. For different particle sizes, this volume exclusion mechanism leads to three regimes of qualitatively different migratory behavior, suggesting applications for separating, trapping, and sorting of particles in three dimensions.

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