论文标题

使用预训练的变压器体系结构从临床笔记中提取心绞痛症状

Extracting Angina Symptoms from Clinical Notes Using Pre-Trained Transformer Architectures

论文作者

Eisman, Aaron S., Shah, Nishant R., Eickhoff, Carsten, Zerveas, George, Chen, Elizabeth S., Wu, Wen-Chih, Sarkar, Indra Neil

论文摘要

生气症状可能意味着心脏风险增加,需要改变心血管管理。这项研究评估了使用在域特异性语料库上微调的变形金刚语言模型中的双向编码器中提取这些症状的潜力。包括未知的动脉粥样硬化心血管疾病的连续患者的459个专家注释的初级保健医师注释的现有病史。注释注释,以提及胸痛和呼吸急促的正面和负面提及。结果表明,在劳累时胸部疼痛或不适,胸部疼痛,呼吸急促以及劳累呼吸困难的检测表现出很高的灵敏度和特异性。小样本量有限的提取因子与胸痛的挑衅和抑制有关。这项研究为医师笔记的自然语言处理提供了一个有希望的起点,以表征临床上可起作用的角质症状。

Anginal symptoms can connote increased cardiac risk and a need for change in cardiovascular management. This study evaluated the potential to extract these symptoms from physician notes using the Bidirectional Encoder from Transformers language model fine-tuned on a domain-specific corpus. The history of present illness section of 459 expert annotated primary care physician notes from consecutive patients referred for cardiac testing without known atherosclerotic cardiovascular disease were included. Notes were annotated for positive and negative mentions of chest pain and shortness of breath characterization. The results demonstrate high sensitivity and specificity for the detection of chest pain or discomfort, substernal chest pain, shortness of breath, and dyspnea on exertion. Small sample size limited extracting factors related to provocation and palliation of chest pain. This study provides a promising starting point for the natural language processing of physician notes to characterize clinically actionable anginal symptoms.

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