论文标题
由单个多嵌段共聚物链形成的新型异质结构
A novel heterogeneous structure formed by a single multiblock copolymer chain
论文作者
论文摘要
我们研究了由单个$（AB）_K $多嵌段共聚物链形成的结构，其中A型珠之间的相互作用纯粹是排斥的，而B型珠倾向于聚集。我们研究了A型珠和B型珠之间的吸引力如何影响链的结构。我们发现了平衡的球状结构的形成，该结构具有独特的异质棋盘板样分布的接触密度分布。与通常由单个$（AB）_K $多嵌段共聚物链形成的结构不同，该结构在A和B块的边界上具有接触式富集。该结构是由多块共聚物链形成的，在该链中，B型珠最多可以用A型或B型珠形成两种可逆键，A型珠最大地形成了一个可逆的键，并与B型珠，以及A-type Beads之间的相互作用纯净。与这种类型的内部相互作用的多块共聚物链可以在各种生物体中建模染色质结构。
We studied structures formed by a single $(AB)_k$ multiblock copolymer chain, in which interaction between A-type beads was purely repulsive, and B-type beads tended to aggregate. We studied how attraction between A-type beads and B-type beads affected the structure of the chain. We discovered formation of an equilibrium globular structure, which had unique heterogeneous checkerboard-like distribution of contact density. Unlike the structures usually formed by a single $(AB)_k$ multiblock copolymer chain, this structure had contact enrichment at the boundaries of A and B blocks. This structure was formed by a multiblock copolymer chain, in which B-type beads could form maximum two reversible bonds either with A-type or B-type beads, A-type beads could form maximum one reversible bond with a B-type bead, and interactions between A-type beads were purely repulsive. Multiblock copolymer chains with this type of intrachain interactions can model structure of chromatin in various organisms.
