论文标题
种子库原理:从休眠中出现的复杂性
Principles of seed banks: complexity emerging from dormancy
论文作者
论文摘要
在整个生命之树中,人口通过锻炼休眠来发展与次优条件相抗衡的能力,从而使个人进入了代谢活性降低的可逆状态。由此产生的种子库是复杂的,存储信息并赋予记忆,从而导致多尺度结构和网络,这些结构涵盖了细胞的集合到整个生态系统。我们概述了与休眠和种子库相关的基本属性和新兴现象,并具有基于统一和数学的框架的愿景,可以解决从全球变化到癌症生物学的生命科学问题。
Across the tree of life, populations have evolved the capacity to contend with suboptimal conditions by engaging in dormancy, whereby individuals enter a reversible state of reduced metabolic activity. The resulting seed banks are complex, storing information and imparting memory that gives rise to multi-scale structures and networks spanning collections of cells to entire ecosystems. We outline the fundamental attributes and emergent phenomena associated with dormancy and seed banks, with the vision for a unifying and mathematically based framework that can address problems in the life sciences, ranging from global change to cancer biology.