论文标题

学习可解释的干预措施,以减轻印度五个州的性工作者的艾滋病毒传播

Learning Explainable Interventions to Mitigate HIV Transmission in Sex Workers Across Five States in India

论文作者

Awasthi, Raghav, Patel, Prachi, Joshi, Vineet, Karkal, Shama, Sethi, Tavpritesh

论文摘要

女性性工作者(FSW)是社会上最脆弱,最污名化的群体之一。结果,他们经常缺乏获得质量的护理机会。从事改善卫生服务的基层组织通常面临着提高由于复杂影响而提高干预措施的挑战。这项工作结合了结构学习,歧视性建模和基层水平的专业知识,即在五个不同的印度州设计干预措施,以发现非明显因素对改善FSW中的安全性实践的影响。学会了一个自举,合奏平均的贝叶斯网络结构,以量化可以最大化避孕套使用的因素,如该模型所揭示的那样。然后,使用XGBoost和随机森林构建了一个判别模型,以预测避孕套的使用行为,最佳模型达到了83%的灵敏度,99%的特异性,而在Precision-Recall曲线下进行预测。生成和歧视性建模方法都表明,金融素养培训是FSW中避孕套使用的主要影响力和预测指标。这些见解导致目前正在进行的现场试验,以评估这种方法的现实效用。我们的工作强调了在资源有限的环境中,在女性性工作者中透明发现和优先考虑反HIV干预措施的可解释模型的潜力。

Female sex workers(FSWs) are one of the most vulnerable and stigmatized groups in society. As a result, they often suffer from a lack of quality access to care. Grassroot organizations engaged in improving health services are often faced with the challenge of improving the effectiveness of interventions due to complex influences. This work combines structure learning, discriminative modeling, and grass-root level expertise of designing interventions across five different Indian states to discover the influence of non-obvious factors for improving safe-sex practices in FSWs. A bootstrapped, ensemble-averaged Bayesian Network structure was learned to quantify the factors that could maximize condom usage as revealed from the model. A discriminative model was then constructed using XgBoost and random forest in order to predict condom use behavior The best model achieved 83% sensitivity, 99% specificity, and 99% area under the precision-recall curve for the prediction. Both generative and discriminative modeling approaches revealed that financial literacy training was the primary influence and predictor of condom use in FSWs. These insights have led to a currently ongoing field trial for assessing the real-world utility of this approach. Our work highlights the potential of explainable models for transparent discovery and prioritization of anti-HIV interventions in female sex workers in a resource-limited setting.

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