论文标题
神经元振荡器网络中的相位振幅耦合
Phase-Amplitude Coupling in Neuronal Oscillator Networks
论文作者
论文摘要
相位振幅耦合(PAC)描述了这种现象,其中高频振荡的功率随着低频振荡的相变。我们提出了一个模型,该模型解释了PAC在大脑中两个常见的架构中的出现,即,由外部低频输入和两个相互作用的局部振荡驱动的高频神经振荡,具有不同的局部生成的局部生成。我们进一步提出了大脑区域的互连结构,并证明低频阶段同步可以整合由局部PAC调节的高频活动,并控制跨远区域的信息流的方向。
Phase-amplitude coupling (PAC) describes the phenomenon where the power of a high-frequency oscillation evolves with the phase of a low-frequency one. We propose a model that explains the emergence of PAC in two commonly-accepted architectures in the brain, namely, a high-frequency neural oscillation driven by an external low-frequency input and two interacting local oscillations with distinct, locally-generated frequencies. We further propose an interconnection structure for brain regions and demonstrate that low-frequency phase synchrony can integrate high-frequency activities regulated by local PAC and control the direction of information flow across distant regions.