论文标题

一种适用于传染病的预后动态模型,可轻松可视化指南 - 英国Covid-19的案例研究

A prognostic dynamic model applicable to infectious diseases providing easily visualized guides -- A case study of COVID-19 in the UK

论文作者

Zhang, Yuxuan, Gong, Chen, Li, Dawei, Wang, Zhi-Wei, Pu, Shengda D, Robertson, Alex W, Yu, Hong, Parrington, John

论文摘要

在不同疾病控制策略下,对传染病传播过程的合理预测是决策者的重要参考点。在这里,我们通过Python建立了动态​​传播模型,并实现了对疾病控制措施的全面调节。我们将政府干预措施分为三类,并引入了三个参数作为疾病控制的关键点的描述,这些参数是区域内增长率,区域间沟通率和感染者的检测率。我们的模拟预测,英国Covid-19的感染将在73天之内失控而无需进行任何干预措施。同时,牛群免疫获得将从中心开始。在我们引入政府干预措施之后,单一干预在疾病控制方面有效,但巨额费用虽然合并干预措施将更有效,其中增强检测数量对于COVID-19的控制策略至关重要。此外,我们根据实际情况下的感染数量计算了最有效的疫苗接种策略的要求。我们的模型是使用迭代算法编程的,并通过细胞自动机对可视化,如果输入基本参数,它可以应用于其他区域的类似流行病,并且能够合成模仿传染病控制中多个因素的效果。

A reasonable prediction of infectious diseases transmission process under different disease control strategies is an important reference point for policy makers. Here we established a dynamic transmission model via Python and realized comprehensive regulation of disease control measures. We classified government interventions into three categories and introduced three parameters as descriptions for the key points in disease control, these being intraregional growth rate, interregional communication rate, and detection rate of infectors. Our simulation predicts the infection by COVID-19 in the UK would be out of control in 73 days without any interventions; at the same time, herd immunity acquisition will begin from the epicentre. After we introduced government interventions, single intervention is effective in disease control but at huge expense while combined interventions would be more efficient, among which, enhancing detection number is crucial in control strategy of COVID-19. In addition, we calculated requirements for the most effective vaccination strategy based on infection number in real situation. Our model was programmed with iterative algorithms, and visualized via cellular automata, it can be applied to similar epidemics in other regions if the basic parameters are inputted, and is able to synthetically mimick the effect of multiple factors in infectious disease control.

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