论文标题
使用遗传数据来建立有关人群历史的直觉
Using Genetic Data to Build Intuition about Population History
论文作者
论文摘要
现在,遗传数据通常用于研究人口大小,细分和基因流的历史。可以使用多种形式的统计方法来测试数据和拟合模型。然而,通常不清楚哪些假设值得测试,哪些值得适合。需要使用较低的形式方法,可以用于遗传数据的探索性分析。解决此问题的一种方法使用 *核苷酸位点模式 *,可简单地摘要遗传数据中的模式。本文展示了如何在探索性数据分析中使用它们。
Genetic data are now routinely used to study the history of population size, subdivision, and gene flow. A variety of formal statistical methods is available for testing hypotheses and fitting models to data. Yet it is often unclear which hypotheses are worth testing, which models worth fitting. There is a need for less formal methods that can be used in exploratory analysis of genetic data. One approach to this problem uses *nucleotide site patterns*, which provide a simple summary of the pattern in genetic data. This article shows how to use them in exploratory data analysis.