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Despite the recent advancement of Generative Adversarial Networks (GANs) in learning 3D-aware image synthesis from 2D data, existing methods fail to model indoor scenes due to the large diversity of room layouts and the objects inside. We argue that indoor scenes do not have a shared intrinsic structure, and hence only using 2D images cannot adequately guide the model with the 3D geometry. In this work, we fill in this gap by introducing depth as a 3D prior. Compared with other 3D data formats, depth better fits the convolution-based generation mechanism and is more easily accessible in practice. Specifically, we propose a dual-path generator, where one path is responsible for depth generation, whose intermediate features are injected into the other path as the condition for appearance rendering. Such a design eases the 3D-aware synthesis with explicit geometry information. Meanwhile, we introduce a switchable discriminator both to differentiate real v.s. fake domains and to predict the depth from a given input. In this way, the discriminator can take the spatial arrangement into account and advise the generator to learn an appropriate depth condition. Extensive experimental results suggest that our approach is capable of synthesizing indoor scenes with impressively good quality and 3D consistency, significantly outperforming state-of-the-art alternatives.