论文标题
固有信号的功能性光学一致性断层扫描学：最新的发展和部署挑战
Functional Optical Coherence Tomography for Intrinsic Signal Optoretinography: Recent Developments and Deployment Challenges
论文作者
论文摘要
视网膜的固有光信号（IOS）成像，也称为选心术（ORG），有望进行视网膜功能客观评估的无创方法。通过提供无与伦比的能力来区分视网膜的各个层，已经积极研究了用于固有信号组织测量值的功能性光学相干断层扫描（OCT）。但是，由于缺乏标准化成像方案以及iOS源和机制的并发症，定量组织功能OCT的临床部署仍然具有挑战性。本文旨在总结ORG测量功能OCT的最新发展，OCT强度和基于阶段的iOS处理。讨论了定量iOS分析和组织解释的技术挑战和观点。
Intrinsic optical signal (IOS) imaging of the retina, also termed as optoretinography (ORG), promises a noninvasive method for objective assessment of retinal function. By providing unparalleled capability to differentiate individual layers of the retina, functional optical coherence tomography (OCT) has been actively investigated for intrinsic signal ORG measurements. However, clinical deployment of functional OCT for quantitative ORG is still challenging due to the lack of a standardized imaging protocol and the complication of IOS sources and mechanisms. This article aims to summarize recent developments of functional OCT for ORG measurement, OCT intensity- and phase-based IOS processing. Technical challenges and perspectives of quantitative IOS analysis and ORG interpretations are discussed.
