论文标题
可激发细胞网络模型中多样性和噪声之间的相互作用
The interplay between diversity and noise in an excitable cell network model
论文作者
论文摘要
我们研究了Fitzhugh-Nagumo元素的3D网络中的多样性和噪声之间的相互作用，拓扑和尺寸选择为胰腺β细胞群集建模，作为令人兴奋的细胞网络的一个例子。我们的结果表明，多样性和噪声不是疾病的等效来源，而是对网络动态的影响不同。与网络元素的固有振荡范围相比，它们的同步机制可能会独立于彼此或协同作用，这取决于多样性分布的平均值。
We study the interplay between diversity and noise in a 3D network of FitzHugh-Nagumo elements, with topology and dimensions chosen to model a pancreatic beta-cell cluster, as an example of an excitable cell network. Our results show that diversity and noise are not equivalent sources of disorder but have different effects on network dynamics. Their synchronization mechanisms may act independently of one another or synergistically, depending on the mean value of the diversity distribution compared to the intrinsic oscillatory range of the network elements.
