论文标题
增强散射介质内部成像的斑点统计信息
Enhancing Speckle Statistics for Imaging inside Scattering Media
论文作者
论文摘要
我们利用记忆效应的斑点相关性来对散射组织后面的不相干线性(单光子)荧光源进行成像。虽然过去对基于内存效应的成像技术进行了大量研究,但对于较厚的散射层和复杂的照明模式,这些相关性很弱,从而限制了该想法的实践适用性。在这项工作中,我们在组织样品和成像传感器之间引入了空间光调制器(SLM),并捕获斑点模式的多个调制。我们表明,通过正确设计调制模式和重建算法,我们可以大大增强数据中的统计相关性。我们利用这一点来证明散射组织后面的大像素宽荧光模式的重建。
We exploit memory effect speckle correlations for the imaging of incoherent linear (single-photon) fluorescent sources behind scattering tissue. While memory effect-based imaging techniques have been heavily studied in the past, for thick scattering layers and complex illumination patterns these correlations are weak, limiting the practice applicability of the idea. In this work, we introduce a Spatial Light Modulator (SLM) between the tissue sample and the imaging sensor and capture multiple modulations of the speckle pattern. We show that by correctly designing the modulation pattern and the reconstruction algorithm we can greatly enhance statistical correlations in the data. We exploit this to demonstrate the reconstruction of mega-pixel wide fluorescent patterns behind scattering tissue.