论文标题
高级扩散加权成像的配对相和幅度重建
A Paired Phase and Magnitude Reconstruction for Advanced Diffusion-Weighted Imaging
论文作者
论文摘要
目的:多拍交错的回声刨花成像可以获得具有高空间分辨率和低畸变的扩散加权图像(DWI),但遭受了镜头之间相位变化引入的幽灵伪影。在这项工作中,我们旨在解决在镜头之间的射击和低信噪比之间的挑战重建。方法:提出了具有配对相和幅度先验的显式相模型,以使重建(PAIR)正规化。前者的先验是从射击阶段的平滑度中得出的,并且在K空间域中以低级别的速度执行。后者探索了多B值和多方向DWI之间具有相似的边缘,图像域中具有加权总变化。结果:广泛的仿真和体内结果表明,对在大量射击(8张镜头)下可以很好地去除幽灵伪像,并在超高的B值(4000 s/mm2)下显着抑制噪声。结论:与互补先验的显式相模对对在镜头之间的挑战性重建方面具有良好的性能,在射击和低信噪比之间的射击运动下具有良好的性能。意义:对在晚期临床DWI应用和大脑功能研究中具有巨大的潜力。
Objective: Multi-shot interleaved echo planer imaging can obtain diffusion-weighted images (DWI) with high spatial resolution and low distortion, but suffers from ghost artifacts introduced by phase variations between shots. In this work, we aim at solving the challenging reconstructions under inter-shot motions between shots and a low signal-to-noise ratio. Methods: An explicit phase model with paired phase and magnitude priors is proposed to regularize the reconstruction (PAIR). The former prior is derived from the smoothness of the shot phase and enforced with low-rankness in the k-space domain. The latter explores similar edges among multi-b-value and multi-direction DWI with weighted total variation in the image domain. Results: Extensive simulation and in vivo results show that PAIR can remove ghost artifacts very well under a high number of shots (8 shots) and significantly suppress the noise under the ultra-high b-value (4000 s/mm2). Conclusion: The explicit phase model PAIR with complementary priors has a good performance on challenging reconstructions under inter-shot motions between shots and a low signal-to-noise ratio. Significance: PAIR has great potential in advanced clinical DWI applications and brain function research.