论文标题
正电子发射断层扫描中单个散射事件的反应线的虚拟外推技术
Virtual extrapolation technique for retracing line of response of single scattered events in positron emission tomography
论文作者
论文摘要
目的:散射现象会在正电子发射断层扫描(PET)中产生降解效应,并且常规拒绝相应的事件。我们提出了一个数学模型,以追溯单个偶然事件的原始响应线,目的是将这些事件纳入PET。 方法:我们已经根据概率密度函数的概念设计了一种新的虚拟外推技术。通过其中,我们将一致光子对的原始两参数列表模式数据转换为一个参数数据集。数据分析中采用了随机抽样和采样分布的过程 - 利用某些独特的属性(例如集体差异和长度补偿)。我们研究了探测器的有限时间和能量分辨率对所提出模型性能的影响。 结果:我们确定了对应于真实和虚拟散射点的数据值的发生频率{放置在以恒定散射角度绘制的圆圈上 - 观察最高计数。正如预期的那样,我们发现了实际散射点位置的最高计数。评估了该模型的均匀衰减幻影培养基。对于理想时间和能源信息的情况,发现结果令人印象深刻,而对于有限决议的情况则少。 结论:我们的工作概述了一种全新的方法;但是,其实用程序需要更加复杂。尽管如此,这种技术似乎很有希望,可以开发一种潜在的方法来提高宠物成像的敏感性。
Purpose: The scattering phenomenon creates degrading effects in positron emission tomography (PET) and the corresponding events are rejected conventionally. We have proposed a mathematical model to retrace the original line of response of the single-scattered coincident events with the aim to incorporate such events in PET. Methods: We have devised a new Virtual extrapolation technique based on the concept of the probability density functions. Through which we transformed the original two-parameter list mode data for the coincident photon pairs to a one-parameter data set. The procedure of random sampling and sampling distribution - by utilizing some unique properties like a collective difference and the length compensation - was employed in the data analysis. We studied the effect of finite timing and energy resolution of detectors on the performance of the proposed model. Results: We determined the frequency of occurrence of the data values corresponding to real as well as fictitious scattering points { placed on the arc of a circle drawn with the constant scattering angle - to observe the highest counts. As expected, we found the highest counts at the location of real scattering points. The model was evaluated for a uniform attenuating phantom medium. The results were found impressive for the case of ideal time and energy information, less so for the cases of finite resolutions. Conclusions: Our work outlines a completely new approach; though, a lot more sophistication is required for its practical utility. Nonetheless, the technique seems promising in developing a potential approach to improve the sensitivity of PET imaging.