论文标题

乳腺癌筛查的多视图超复杂学习

Multi-View Hypercomplex Learning for Breast Cancer Screening

论文作者

Lopez, Eleonora, Grassucci, Eleonora, Valleriani, Martina, Comminiello, Danilo

论文摘要

传统上,乳腺癌分类的深度学习方法进行了单视图分析。然而,放射科医生同时分析了组成乳房X线摄影检查的所有四种观点,这是由于乳房X线摄影观点中所包含的相关性,这些视图中的相关性提出了至关重要的信息,以识别肿瘤。鉴于此,一些研究开始提出多视图方法。然而,在这种现有的体系结构中,乳房X线图视图是通过单独的卷积分支作为独立图像处理的,因此失去了相关性。为了克服这种局限性,在本文中,我们提出了一种基于参数化超复杂神经网络的多视乳腺癌分类的方法学方法。多亏了超复杂的代数属性,我们的网络能够建模并利用构成乳房X线照片的不同视图之间的现有相关性,从而模仿临床医生执行的阅读过程。之所以发生这种情况,是因为超复杂网络将两个全局属性作为标准神经模型以及局部关系(即实数网络在建模时都无法实现的视图相关性)捕获。我们定义了旨在处理两次观察考试的体系结构,即Phresnets和四视图考试,即Physenet和Phybonet。通过对公开可用数据集进行的广泛的实验评估,我们证明了我们提出的模型显然超过了现实价值的对应物和最先进的方法,证明乳腺癌的分类受益于拟议中的多视图体系结构。我们还通过考虑不同的基准以及诸如分割等更精细的任务来评估乳房X线图分析以外的方法可推广性。 https://github.com/ispamm/phbreast可以免费获得,可免费获得,以供我们实验的完整代码和预估计的模型。

Traditionally, deep learning methods for breast cancer classification perform a single-view analysis. However, radiologists simultaneously analyze all four views that compose a mammography exam, owing to the correlations contained in mammography views, which present crucial information for identifying tumors. In light of this, some studies have started to propose multi-view methods. Nevertheless, in such existing architectures, mammogram views are processed as independent images by separate convolutional branches, thus losing correlations among them. To overcome such limitations, in this paper, we propose a methodological approach for multi-view breast cancer classification based on parameterized hypercomplex neural networks. Thanks to hypercomplex algebra properties, our networks are able to model, and thus leverage, existing correlations between the different views that comprise a mammogram, thus mimicking the reading process performed by clinicians. This happens because hypercomplex networks capture both global properties, as standard neural models, as well as local relations, i.e., inter-view correlations, which real-valued networks fail at modeling. We define architectures designed to process two-view exams, namely PHResNets, and four-view exams, i.e., PHYSEnet and PHYBOnet. Through an extensive experimental evaluation conducted with publicly available datasets, we demonstrate that our proposed models clearly outperform real-valued counterparts and state-of-the-art methods, proving that breast cancer classification benefits from the proposed multi-view architectures. We also assess the method generalizability beyond mammogram analysis by considering different benchmarks, as well as a finer-scaled task such as segmentation. Full code and pretrained models for complete reproducibility of our experiments are freely available at https://github.com/ispamm/PHBreast.

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