论文标题
脉冲真空弧沉积氮掺杂的钻石涂层，用于静电传播多丙酮酸支架的长期亲水性
Pulsed vacuum arc deposition of nitrogen-doped diamond-like coatings for long-term hydrophilicity of electrospun polycaprolactone scaffolds
论文作者
论文摘要
聚（$ε$ -Caprolactone）电纺支架的表面疏水性阻止了它们与细胞和组织整合的相互作用。脚手架的血浆处理增强了其亲水性。但是，支架的疏水性在大约30天内恢复。在这种交流中，我们报告了多丙酮酸酮支架接下达6个月以上的可能性。为此，使用脉冲真空弧沉积技术在氮气大气中使用石墨靶标的脉冲真空弧沉积技术沉积在支架表面上。已经确定可以保留支架结构的单侧修改。钻石样涂料组合物（SP2/SP3杂交碳比）可与氮气压调谐。成纤维细胞培养的体外测试未揭示样品提取物中的任何细胞毒性化合物。
The surface hydrophobicity of poly($ε$-caprolactone) electrospun scaffolds prevents their interactions with cells and tissue integration. Plasma treatment of the scaffolds enhances their hydrophilicity. However, the hydrophobicity of scaffolds is restored in about 30 days. In this communication, we report the possibility of polycaprolactone electrospun scaffolds hydrophilization for more than 6 months. For that, diamond-like coating was deposited on the scaffolds surface using pulsed vacuum arc deposition technique in nitrogen atmosphere with sputtering of graphite target. It was established that single-side modification preserving scaffold structure is possible. The diamond-like coatings composition (sp2/sp3 hybridized carbon ratio) was tunable with nitrogen pressure. In vitro tests with fibroblasts cell culture did not reveal any cytotoxic compounds in the samples extracts.
