论文标题
超分辨率宠物的准监督学习
Quasi-supervised Learning for Super-resolution PET
论文作者
论文摘要
正电子发射断层扫描(PET)的低分辨率限制了其诊断性能。深度学习已成功应用于实现超分辨率宠物。但是,在这种情况下,常用的监督学习方法需要许多低分辨率和高分辨率(LR和HR)PET图像。尽管无监督的学习利用了未配对的图像,但结果并不像受到监督深度学习的结果那样好。在本文中,我们提出了一种准监督的学习方法,该方法是一种新型的弱监督学习方法,通过利用未配对的LR和HR图像贴片之间的相似性来从LR对应物中恢复HR PET图像。具体而言,LR图像贴片是从患者作为输入的,而来自其他患者的最相似的HR斑块作为标签。匹配的HR和LR补丁之间的相似性是网络构建的先验。我们提出的方法可以通过设计新网络或修改现有网络来实现。作为这项研究的一个例子,我们已修改了超分辨率PET的周期一致生成对抗网络(Cyclegan)。我们的数值和实验结果在定性和定量上表明了我们方法相对于先进方法的优点。该代码可在https://github.com/pigyang-ops/cyclegan-qsdl上公开获取。
Low resolution of positron emission tomography (PET) limits its diagnostic performance. Deep learning has been successfully applied to achieve super-resolution PET. However, commonly used supervised learning methods in this context require many pairs of low- and high-resolution (LR and HR) PET images. Although unsupervised learning utilizes unpaired images, the results are not as good as that obtained with supervised deep learning. In this paper, we propose a quasi-supervised learning method, which is a new type of weakly-supervised learning methods, to recover HR PET images from LR counterparts by leveraging similarity between unpaired LR and HR image patches. Specifically, LR image patches are taken from a patient as inputs, while the most similar HR patches from other patients are found as labels. The similarity between the matched HR and LR patches serves as a prior for network construction. Our proposed method can be implemented by designing a new network or modifying an existing network. As an example in this study, we have modified the cycle-consistent generative adversarial network (CycleGAN) for super-resolution PET. Our numerical and experimental results qualitatively and quantitatively show the merits of our method relative to the state-ofthe-art methods. The code is publicly available at https://github.com/PigYang-ops/CycleGAN-QSDL.