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At transitions between phases of matter, physical systems can exhibit universal behavior independent of their microscopic details. Probing such behavior in quantum many-body systems is a challenging and practically important problem that can be solved by quantum computers, potentially exponentially faster than by classical computers. In this work, we use the Quantinuum H1-1 quantum computer to realize a quantum extension of a simple classical disease spreading process that is known to exhibit a non-equilibrium phase transition between an active and absorbing state. Using techniques such as qubit-reuse and error avoidance based on real-time conditional logic (utilized extensively in quantum error correction), we are able to implement large instances of the model with $73$ sites and up to $72$ circuit layers, and quantitatively determine the model's critical properties. This work demonstrates how quantum computers capable of mid-circuit resets, measurements, and conditional logic enable the study of difficult problems in quantum many-body physics: the simulation of open quantum system dynamics and non-equilibrium phase transitions.