论文标题

传输强度,死亡率和经济的相互作用:对1900的大流行的回顾性分析

The interaction of transmission intensity, mortality, and the economy: a retrospective analysis of the COVID-19 pandemic

论文作者

Morgenstern, Christian, Laydon, Daniel J., Whittaker, Charles, Mishra, Swapnil, Haw, David, Bhatt, Samir, Ferguson, Neil M.

论文摘要

迄今为止,Covid-19-19造成了超过640万次注册死亡,并对经济活动产生了深远的影响。在这里,我们研究了2020年1月至2022年12月25日在25个欧洲国家的SARS-COV-2大流行期间传播,死亡率和经济的相互作用。我们采用具有自动回归术语的贝叶斯混合效应模型。我们发现,疾病传播强度的增加会降低国内生产总值(GDP)并增加每日过量死亡,而与GDP相比,对多余死亡的持久影响更长,这会更快地恢复。从广义上讲,我们的结果加强了直觉现象,即重要的经济活动来自各种各样的人与人之间的互动。我们报告非药物干预措施(NPI)对传播强度,过量死亡和GDP变化的有效性以及对政策制定者的影响。我们的结果突出了单个NPI的复杂成本效益。例如,禁止国际旅行会增加GDP并减少多余的死亡。我们认为国家随机影响及其与GDP和过量死亡的过多变化的关联。例如,欧洲较发达国家通常对19009年大流行,优先考虑医疗保健以及与经济绩效的过多死亡有关。长期的经济障碍并未被我们的模型以及长期疾病的影响(长期相互作用)完全捕获。我们的结果强调,疾病对一个国家的影响是复杂且多方面的,简单的启发式结论以从经济和疾病负担中提取最佳结果是具有挑战性的。

The COVID-19 pandemic has caused over 6.4 million registered deaths to date and has had a profound impact on economic activity. Here, we study the interaction of transmission, mortality, and the economy during the SARS-CoV-2 pandemic from January 2020 to December 2022 across 25 European countries. We adopt a Bayesian Mixed Effects model with auto-regressive terms. We find that increases in disease transmission intensity decreases Gross domestic product (GDP) and increases daily excess deaths, with a longer lasting impact on excess deaths in comparison to GDP, which recovers more rapidly. Broadly, our results reinforce the intuitive phenomenon that significant economic activity arises from diverse person-to-person interactions. We report on the effectiveness of non-pharmaceutical interventions (NPIs) on transmission intensity, excess deaths, and changes in GDP, and resulting implications for policy makers. Our results highlight a complex cost-benefit trade off from individual NPIs. For example, banning international travel increases GDP and reduces excess deaths. We consider country random effects and their associations with excess changes in GDP and excess deaths. For example, more developed countries in Europe typically had more cautious approaches to the COVID-19 pandemic, prioritising healthcare, and excess deaths over economic performance. Long term economic impairments are not fully captured by our model, as well as long term disease effects (Long Covid). Our results highlight that the impact of disease on a country is complex and multifaceted, and simple heuristic conclusions to extract the best outcome from the economy and disease burden are challenging.

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