论文标题

关于青少年运动参与对成年早期健康影响的观察性研究的分析方案

Pre-analysis protocol for an observational study on the effects of adolescent sports participation on health in early adulthood

论文作者

Kokandakar, Ajinkya H, Lin, Yuzhou, Jin, Steven, Weiss, Jordan, Rabinowitz, Amanda R, May, Reuben A Buford, Small, Dylan, Deshpande, Sameer K

论文摘要

我们将使用国家青年和宗教研究中的纵向数据研究青少年体育参与对健康早期健康的影响。我们专注于23--28岁的两个主要结果 - 自我评价的健康和PHQ9患者抑郁症问卷的总成绩 - 以及控制与人口统计学和家庭社会经济状况有关的几个潜在混杂因素。将体育参与者与匹配的非运动参与者与类似混杂的人进行比较。不幸的是,基于如此广泛的暴露的分析无法探讨参与某些类型的运动(例如,足球或足球等碰撞运动)的可能性可能比其他运动对健康产生更大的影响。 在这项研究中,我们介绍了暴露定义的层次结构,从广泛的(参加任何课后活动)到狭窄(例如,参与有限接触运动)。我们将对每个定义进行单独的匹配观测研究,以估算几个体育参与级别的健康影响。为了在保持固定的家庭错误率的同时进行这些研究,我们采用了有序的测试方法,利用了暴露定义之间的逻辑关系。我们的研究还将考虑几个次要结果,包括体重指数,生活满意度和有问题的饮酒行为。

We will study the impact of adolescent sports participation on early-adulthood health using longitudinal data from the National Study of Youth and Religion. We focus on two primary outcomes measured at ages 23--28 -- self-rated health and total score on the PHQ9 Patient Depression Questionnaire -- and control for several potential confounders related to demographics and family socioeconomic status. Comparing outcomes between sports participants and matched non-sports participants with similar confounders is straightforward. Unfortunately, an analysis based on such a broad exposure cannot probe the possibility that participation in certain types of sports (e.g., collision sports like football or soccer) may have larger effects on health than others. In this study, we introduce a hierarchy of exposure definitions, ranging from broad (participation in any after-school organized activity) to narrow (e.g., participation in limited-contact sports). We will perform separate matched observational studies, one for each definition, to estimate the health effects of several levels of sports participation. In order to conduct these studies while maintaining a fixed family-wise error rate, we deployed an ordered testing approach that exploits the logical relationships between exposure definitions. Our study will also consider several secondary outcomes including body mass index, life satisfaction, and problematic drinking behavior.

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