论文标题

在美国,儿童疫苗接种的空间分布和决定因素拒绝

Spatial distribution and determinants of childhood vaccination refusal in the United States

论文作者

Kang, Bokgyeong, Goldlust, Sandra, Lee, Elizabeth C., Hughes, John, Bansal, Shweta, Haran, Murali

论文摘要

近年来,父母拒绝和延迟儿童疫苗接种的情况有所增加。这种现象挑战了维持牛群免疫力,并增加了疫苗预防疾病爆发的风险。我们检查了我们从行政医疗保健数据集收集的五岁以下患者的县级疫苗拒绝。我们用贝叶斯零发出的负面二项式回归模型对这些数据进行建模,以捕获与疫苗拒绝拒绝相关的社会和政治过程,以及影响我们测量疫苗拒绝拒绝的因素。您的工作突出了精细的社会人口学特征,这些特征与疫苗的拒绝相关,可以通过抗反复的发展来依赖于疫苗,从而在抗逆转录状态下,在抗反复的方面,与抗反复关系相关,并在抗空中解释了依从性,并且在抗反复的方面,与抗疫苗的开发相关。优化疫苗摄取的公共卫生策略。

Parental refusal and delay of childhood vaccination has increased in recent years in the United States. This phenomenon challenges maintenance of herd immunity and increases the risk of outbreaks of vaccine-preventable diseases. We examine US county-level vaccine refusal for patients under five years of age collected during the period 2012--2015 from an administrative healthcare dataset. We model these data with a Bayesian zero-inflated negative binomial regression model to capture social and political processes that are associated with vaccine refusal, as well as factors that affect our measurement of vaccine refusal.Our work highlights fine-scale socio-demographic characteristics associated with vaccine refusal nationally, finds that spatial clustering in refusal can be explained by such factors, and has the potential to aid in the development of targeted public health strategies for optimizing vaccine uptake.

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