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Weakly supervised semantic segmentation (WSSS) with image-level labels is a challenging task. Mainstream approaches follow a multi-stage framework and suffer from high training costs. In this paper, we explore the potential of Contrastive Language-Image Pre-training models (CLIP) to localize different categories with only image-level labels and without further training. To efficiently generate high-quality segmentation masks from CLIP, we propose a novel WSSS framework called CLIP-ES. Our framework improves all three stages of WSSS with special designs for CLIP: 1) We introduce the softmax function into GradCAM and exploit the zero-shot ability of CLIP to suppress the confusion caused by non-target classes and backgrounds. Meanwhile, to take full advantage of CLIP, we re-explore text inputs under the WSSS setting and customize two text-driven strategies: sharpness-based prompt selection and synonym fusion. 2) To simplify the stage of CAM refinement, we propose a real-time class-aware attention-based affinity (CAA) module based on the inherent multi-head self-attention (MHSA) in CLIP-ViTs. 3) When training the final segmentation model with the masks generated by CLIP, we introduced a confidence-guided loss (CGL) focus on confident regions. Our CLIP-ES achieves SOTA performance on Pascal VOC 2012 and MS COCO 2014 while only taking 10% time of previous methods for the pseudo mask generation. Code is available at https://github.com/linyq2117/CLIP-ES.